49ers OT Williams, LB Greenlaw questionable, WR Evans out vs. Cowboys

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• Nick WagonerNov 13, 2026, 05:46 PM ET

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  Nick Wagoner is an NFL reporter at ESPN. Nick has covered the San Francisco 49ers since 2016, having previously covered the St. Louis Rams for 12 years, including three years (2013 to 2015) at ESPN. In over a decade with the company, Nick has led ESPN's coverage of the Niners' 2019 and 2023 Super Bowl run, Colin Kaepernick's protest, the Rams making Michael Sam the first openly gay player drafted to the NFL, Sam's subsequent pursuit of a roster spot and the team's relocation and stadium saga.

SANTA CLARA, Calif. -- The San Francisco 49ers had two important additions to their injury report this week with left tackle Trent Williams (shoulder) and linebacker Dre Greenlaw (knee) now listed as questionable for Sunday's game against the Dallas Cowboys.

According to coach Kyle Shanahan, Williams and Greenlaw suffered their injuries in Thursday's practice, with both players listed as limited for that day because of it. Greenlaw was again limited Friday, while Williams did not practice.

"Anytime you hurt your shoulder on a Thursday, it doesn't make you totally at ease," Shanahan said of Williams. "Sunday comes fast, but hopefully that's enough time for him to be all right."

If Williams is unable to play, the Niners will turn to swing tackle Vederian Lowe to step into the lineup. And if Greenlaw can't play, rookie Jaden Dugger will move into the weakside linebacker spot, according to Shanahan.

"Hopefully we'll have Dre on Sunday, but if we don't, next man up, and our next man's proven himself so far," Shanahan said.

Elsewhere on the injury report, wide receiver Mike Evans (Achilles) will miss his third straight game. He's the only Niner officially ruled out against the Cowboys as he continues to work his way through the tendinitis that flared up in Week 6 against the Washington Commanders.

Shanahan offered a bit more clarity Friday afternoon on when Evans could return, saying there's "a chance" for next week against the Minnesota Vikings but adding that he's "not sure yet."

"It's been going well," Shanahan said. "I'm sure if this was the last game or something, he'd be able to go out there. But we're just trying to make sure it fully heals so it doesn't act up again, but it's going in the right direction."

In addition to Williams and Greenlaw, all three of San Francisco's top cornerbacks -- Deommodore Lenoir (foot), Renardo Green (back) and Upton Stout (shoulder/neck) -- are questionable against the Cowboys.

So, too, are defensive tackle C.J. West (knee) and defensive back Nate Hobbs (adductor), both of whom are working their way back from injured reserve and could be activated Saturday.

Meanwhile, wide receiver Deebo Samuel, who has been out with a hamstring injury since Week 5, practiced all week and is cleared to return against the Cowboys.

"He had a good week, healthy," Shanahan said. "First week back, so he's still getting back into it, but [he] took care of himself real well while he was injured and had a good week."