Pope Leo XI has left the Vatican for an ambitious 12-day trip across South America that is expected to attract millions of people.

The first US-born pope is returning to a Catholic stronghold where he lived for decades as a missionary.

The 71-year-old, who underwent lung cancer surgery last month, will visit Uruguay, Argentina and Peru.

It is on one of the most demanding overseas tours taken by a pope in decades.

Earlier this week, the Vatican said that he had recovered from his operation and that no special precautions were being taken for the tour.

Pope Leo will travel 31,000km across 10 cities and give 36 speeches.

He was born in the US city of Chicago but spent decades in Peru and became a Peruvian citizen.

He considers the visit a "homecoming to places where he spent a long time and to which he feels closely connected," said Vatican spokesperson Matteo Bruni.

Pope Leo said that he was looking forward to returning to countries "so dear to me".

He told pilgrims - at his weekly audience in St Peter's Square on Wednesday - that he hoped the trip would "strengthen the faith, renew hope, (and) rekindle the fire of charity".

Workers in Peru transport a 14 metre-tall sculpture of Pope Leo
A sculpture of Pope Leo in the Peruvian city of Callao

The pope, who departed Fiumicino Airport in Rome early this morning, is due to arrive in Uruguay this evening.

He will stay in Latin America's most security country - and one of the wealthiest - until Sunday, visiting three cities.

A tight security operation is in place, with 5,000 police officers and 1,000 soldiers mobilised.

Pope Leo will be driven along the capital Montevideo's waterfront promenade in a custom-made popemobile, before meeting left-wing President Yamandu Orsi and receiving the keys to the city.

From Uruguay, he will travel to Argentina for three days, before spending six days in Peru.

The pope, who has forcefully decried the direction of global leadership in recent months, will address the governments in each country in closely watched speeches.

He will also lead outdoor masses at major sites, visit a prison in Argentina and head to remote Andean communities in Peru by helicopter.

On Sunday, he will give an address to Argentine President Javier Milei, a right-wing libertarian seen as a close ally to US President Donald Trump, who attacked the pope earlier this year after he criticised the Iran war.

Mr Bruni said the speeches during the tour would address a range of issues facing South America, including environmental destruction, arms trafficking and regional political instability.

"The pope brings a message of communion and unity, an invitation to recognise one another ... as members of one same family," he said.

In the Peruvian capital, Lima, vendors are selling T-shirts and rosaries with his image on them, and Leo bread is on sale in bakeries.

Inmates in a women's prison are crafting dolls in his likeness.

A 14m high sculpture of the pontiff has been erected in the port city of Callao, which he is to visit.

The trip will take him to the former Inca capital of Cusco and the Amazon rainforest.

The pope will also revisit his former life as Robert Francis Prevost, from a supper with priests of his old diocese of Chiclayo to a private visit to a chapel that he helped rebuild.

The late Pope Francis - Pope Leo's predecessor from Argentina - visited Peru in 2018 but never returned home.

A head of the Catholic Church has not visited Argentina or Uruguay since the late 1980s.

Argentine officials have said that seven million people will attend events with the pope.

A map showing details of Pope Leo's visit to South America

Latin America has long been the world's largest Catholic region in absolute numbers, but the church has been losing ground recently to fast-growing evangelical denominations and has struggled to respond to progressive social attitudes and individualised forms of worship.

It hopes the visit can reenergise faith and help repair its standing after abuse scandals tarnished its reputation.

Pope Leo will hold several meetings with survivors of sexual abuse by clergy during the trip, the Vatican said, without yet providing further details.

He was treated last month for lung adenocarcinoma, the most common form of lung cancer.

Doctors said the disease was localised and he would not require any further treatment.

Mr Bruni said that Pope Leo had recovered enough and no additional medical measures would be necessary during the visit.

Source: RTÉ News

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