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Health experts have cautioned against use of the drugs, citing a lack of clinical trials for humans and the unknown long-term effects.

Health and Human Services Secretary Robert F. Kennedy Jr. took steps Wednesday that could open up access to certain unapproved peptide drugs that are being promoted for wellness.

A coroner has found the death of Australian actor Richard Norton was triggered by injecting unapproved peptides, recommending the TGA consider tougher restrictions.

In a unilateral declaration by the health secretary, several injections promoted by online influencers will become widely available. The F.D.A. had advised against the move.

"I came down hard on it," the actress says of the incident.

HHS is pausing legal action against compounding pharmacies that make certain peptides, effectively allowing them to offer the unapproved drugs immediately.

Researchers analyzing nearly 150,000 Reddit posts uncovered unexpected symptom reports linked by users to unapproved versions of retatrutide, including increased appetite, sleep disturbances, and elevated heart rates. The findings differ from clinical trial results and highlight how AI could help identify potential drug safety signals that warrant further in